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UNPLUG PSORIASIS

turn off the lights on psoriasis…

The complex immunopathogenic mechanisms driving psoriasis involve interactions between keratinocytes and immune cells, overloading the cycle of inflammation that keeps patients plugged into their psoriasis – bound by skin plaques causing clinical symptoms of pain, itching, and burning sensations.1,2

…for greater clarity

As we shed light on the intricacies of psoriasis pathogenesis, we now know that other proinflammatory cytokines supplement the IL-17/23 axis and charge the immune cells in circulation.2,3

Flip the switch

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Unplugging the Complex Circuitry of Psoriasis Pathogenesis

Hear expert insights into the evolving understanding of psoriasis pathogenesis, the challenges that patients with moderate-to-severe psoriasis face, and on raising the standard in the management of patients with psoriasis.

ANDREW BLAUVELT, MD, MBA APRIL ARMSTRONG, MD, MPHGEORGE HAN, MD, PhD

This educational webinar was created and funded by UCB

THE COMPLEX IMMUNOPATHOGENIC CIRCUITRY OF PSORIASIS

Our understanding of the complex immunopathogenic mechanisms driving psoriasis continues to be illuminated. Increased clarity on the interactions between keratinocytes and immune cells within the immune circuit sheds light on the cycle of inflammation.3

Learn more about the mechanism of disease

Current unmet needs in psoriasis

Patients with psoriasis experience burden that is beyond skin deep. A number of observational studies and patient surveys showed that not all patients with moderate-to-severe psoriasis are achieving clear skin, which can impact their quality of life. Better understanding of the complex immunopathologic circuitry of psoriasis is needed.

57% of patients being treated for moderate-to-severe plaque psoriasis did not feel that they were achieving clear/almost clear skin.

Only one in four patients achieved complete skin clearance after 6 months of treatment with biologics.5||

94% of patients with moderate-to-severe psoriasis felt that their psoriasis imparted a moderate, large, or very large effect on quality of life.

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